Name and Position

Dr Mark Tremelling
Gastroenterology & General Medicine

Contact Details

Main Telephone Number:01603 288358 and 01603 641190


Department page: Gastroenterology

Speciality: Gastroenterology, General Medicine

Sub-speciality: Inflammatory bowel disease, Colonoscopy

Special clinical interests: Inflammatory bowel diseases, Irritable bowel syndrome, Diagnostic and interventional colonoscopy, Endoscopy training

Research interests: The genetics of inflammatory bowel disease

Secretary: Kim Clapham, Kerry Girdlestone and Chloe Leggett

GMC Number: 4438359

Current membership(s) of professional National and Regional bodies: UK IBD Genetics consortium, Regional IBD Forum

Professional profile: I qualified at St. Mary’s Hospital, Paddington, London 1997, and was appointed as a Specialist Registrar in the Eastern Deanery in 2002. I completed clinical training in gastroenterology and general medicine in Hinchingbrooke, Ipswich, Addenbrooke’s, Norwich and Basildon hospitals. I have been a consultant gastroenterologist at the Norfolk and Norwich University Hospital since February 2010.

I developed my special interest in inflammatory bowel disease (IBD) during a successful 3 year research period in Cambridge in 2005 undertaking molecular research into the genetic basis of IBD both independently and in collaboration with other research groups within the UK. I have also been an investigator in many clinical trials of novel therapies in IBD.

I was awarded an MD by University of London 2009

Publication highlights include:

Tremelling M, Cummings F, Fisher SA
IL23R variation determines susceptibility but not disease phenotype in Inflammatory bowel disease
Gastroenterology 2007; 132: 1657-64

Fisher SA, Tremelling M
Genetic determinants of ulcerative colitis include the ECM1 locus
NATURE GENETICS 2008; 40: 710-12

Tremelling M, Berzuini C, Massey D et al
Contribution of TNFSF15 gene variants to Crohn’s disease susceptibility confirmed in UK panel
Inflammatory Bowel Diseases 2008; 14: 733-7

I intend to continue an active clinical and pre-clinical research interest into factors influencing susceptibility to IBD whilst helping to develop the provision of services for patients with IBD at the Norfolk and Norwich University Hospital.

Personal Profile: Married with 4 children (all boys). Previously keen rugby player, now minis rugby coach. Keen road cyclist, runner and golfer.